Directed adaptation of entomopathogenic fungi
As an alternative to chemical pesticides, entomopathogenic fungi such as Beauveria bassiana and Metarhizium anisopliae are currently under intensive study as promising arthropod pest biological controls agents.
Strains of these fungi have been selected for control of insects and other arthropods that act as disease vectors including mosquitoes and ticks, crops pests such as whiteflies and borers, and ecologically hazardous, invading pests such as fire ants and termites. Despite their potential several factors have hindered widespread adoption of fungi as part of biological control regimes. Effectiveness under laboratory conditions often does not translate to the high mortality needed for biological control under field conditions. Significant impediments include the relatively low resistance of fungi to abiotic stresses such as solar irradiation and heat.
Using the Evolugator, entomopathogenic fungi was adapted for growth from 25°C to 37°C. This technology could be used to adapt fungal strains to virtually any environmental condition including affecting host range.
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